Endoplasmic Reticulum MCQs

We prepared Endoplasmic Reticulum multiple-choice questions (MCQs) covering topics such as its structure, functions, and roles in cellular physiology.
So whether you’re studying for an exam or seeking to deepen your understanding of cell biology, these MCQs provide valuable learning opportunities for students and enthusiasts alike.

Start with MCQs below and expand your knowledge of cellular organelles!

MCQ on Endoplasmic Reticulum

The _ is a series of canals that connects the nucleus to the cytoplasm of the cell.

endoplasmic reticulum (ER)
Centriole
Chloroplast
mitochondria

Correct Answer

endoplasmic reticulum (ER) 

The part of the Endoplasmic Reticulum without ribosomes is called?

Rough ER
smooth ER
Endo ER
Meta ER

Correct Answer

smooth ER

The part of the Endoplasmic Reticulum with ribosomes is called?

Rough ER
smooth ER
Endo ER
Meta ER

Correct Answer

Rough ER

The endoplasmic reticulum (ER) is a complex network of membranes found in eukaryotic cells, involved in various cellular processes such as protein synthesis, lipid metabolism, and calcium storage.

Endoplasmic reticulum (ER) is a series of __ that connects the nucleus to the cytoplasm.
Cytoplasm
Nucleus
Lumen
Canals

Correct Answer

Canals

For term “endoplasmic reticulum” Endo means _

Outside
In between
inside
Side to side

Correct Answer

inside

endoplasmic reticulum cisternal space is also known as _

Cytoplasm
Nucleus
Canals
Lumen

Correct Answer

Lumen

Endoplasmic reticulum serves as a pipeline between the _ and _ .

Nucleus and Lumen
Nucleus and Canals
Nucleus and cytoplasm
Cytoplasm and Lumen

Correct Answer

Nucleus and cytoplasm

Proteins to stay in the lumen and are known as endoplasmic reticulum _ proteins.

Canals
Resident
Transient
Lumen

Correct Answer

Resident 

Transient

Resident protein contain retention signal which is made up of __

Specific sequence of Sulfuric acids
Specific sequence of RNA
Specific sequence of amino acids
Specific sequence of DNA

Correct Answer

Specific sequence of amino acids

reticulum refers to the __ appearance of endoplasmic reticulum

Squarlike
Circlelike
Trianglelike
Netlike

Correct Answer

Netlike

There are __ basic kinds of endoplasmic reticulum

One
Three
Two
Five

Correct Answer

Two

The surface of rough endoplasmic reticulum is covered with __

Golgi apparatus
Ribosomes
Nucleus
Nucleolus

Correct Answer

Ribosomes

__ endoplasmic reticulum involved in production and processing of proteins that will be exported.

Rough
Square
Spherical
Smooth

Correct Answer

Rough, Smooth

Smooth endoplasmic reticulum is also called __

Serrated
Classic
Rough
Traditional

Correct Answer

Traditional

Two types of endoplasmic reticulum are _ and __

Serrated and Classic
Classic and Rough
Rough and Smooth
Rough and Traditional

Correct Answer

Rough and Smooth 

Production of lipids (fats) is associated with _ endoplasmic reticulum

Classic
Rough
Traditional
Smooth

Correct Answer

Smooth

Detoxification of drugs and poisons in cell is assocated with __ endoplasmic reticulum

Classic
Smooth
Rough
Traditional

Correct Answer

Smooth

Brain and liver cells have more extensive __ endoplasmic reticulum

Classic
Smooth
Rough
Traditional

Correct Answer

Smooth

Smooth endoplasmic reticulum also stores _ and is involved in __ metabolism.

Sodium
Nitrogen
Calcium
Potassium

Correct Answer

Calcium

In muscle cells, _ endoplasmic reticulum releases ____to trigger muscle contractions.

Rough, Calcium
Smooth, Calcium
Smooth, Potassium
Rough, Potassium

Correct Answer

Smooth, Calcium 

Information is shared in a very __ manner between endoplasmic reticulum and nucleus.

Slow
Efficient
Moderate
Sometime fast, most of the time slow

Correct Answer

Efficient

What happens if the endoplasmic reticulum begins to undergo functional problems and unfolded proteins accumulate

It sends a signal to Chloroplasts
It sends a signal to chlorophyll
It sends a signal to DNA
It sends a signal to nucleus

Correct Answer

It sends a signal to nucleus 

How does nucleus respond to the call by ER regarding functional problems ?

Shuts down protein production
Slows down protein production
Fasten up protein production
Slows down Vitamin production

Correct Answer

Slows down protein production

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